Blood zinc (plasma, red blood cell zinc) and insulin-like growth factor-1 in children from an "Impoverished" area in Ankara


Cin Ş., ÜNAL E., Pamir A., Koloǧlu B., Çavdar A. O.

Journal of Trace Elements in Experimental Medicine, vol.14, no.1, pp.31-34, 2001 (SCI-Expanded) identifier

  • Publication Type: Article / Abstract
  • Volume: 14 Issue: 1
  • Publication Date: 2001
  • Journal Name: Journal of Trace Elements in Experimental Medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.31-34
  • Keywords: Blood zinc, IGF-1, Poor children
  • Ankara University Affiliated: Yes

Abstract

The study was performed on ninety-five children between the ages 10 to 20 years from an impoverished area (Çukurca) in Ankara, Turkey. Blood zinc (plasma and RBC) concentrations and plasma IGF-1 levels were measured simultaneously. The mean plasma zinc and IGF-1 in the growth retarded group (height <3rd percentile) were lower as compared to those with normal growth. There was a statistically significant difference between plasma IGF-1 levels in these two groups (P < 0.01). There was also a positive correlation between plasma zinc and IGF-1 levels with linear growth in these children from "slum areas" with under-nutrition. Our study provides further confirmation about a relationship between plasma zinc and IGF-1. © 2001 Wiley-Liss, lnc.