COMPARISON OF THE ANTIBACTERIAL EFFICIENCY OF SUPER ANIONIC OXYGEN SOLUTION CONTAINING SILVER NANOPARTICLES (NPAG) AND SUPER ANIONIC OXYGEN SOLUTION (H2O8) AGAINST E. FAECALIS AND S. MUTANS – AN IN VITRO STUDY GÜMÜŞ NANOPARTİKÜLLERİ İÇEREN SÜPER ANYONİK OKSİJEN SOLÜSYONU (NPAG) İLE SÜPER ANYONİK OKSİJEN SOLÜSYONU’NUN (H2O8) E. FAECALİS VE S. MUTANS'A KARŞI ANTİBAKTERİYEL ETKİNLİĞİNİN KARŞILAŞTIRILMASI – İN VİTRO ÇALIŞMA

Göçmen D., EROL H. B., ZIRAMAN F. G., KAŞKATEPE B.

Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.49, sa.3, ss.785-789, 2025 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 3
  • Basım Tarihi: 2025
  • Doi Numarası: 10.33483/jfpau.1601950
  • Dergi Adı: Ankara Universitesi Eczacilik Fakultesi Dergisi
  • Derginin Tarandığı İndeksler: Scopus, Central & Eastern European Academic Source (CEEAS), EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.785-789
  • Anahtar Kelimeler: Biofilms, dentin, endodontics, nanoparticles, root canal irrigants
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: The purpose of this study is to compare the antimicrobial effect of super anionic oxygen solution containing silver nanoparticles (NpAg) and super anionic oxygen solution (H2O8) in vitro Material and Method: “The antimicrobial activity of the solutions was tested against Enterococcus faecalis ATCC 29212 (E. faecalis) and Streptococcus mutans ATCC 25175 (S. mutans) standart bacteria. The effects of them applied on the bacterial suspension after 10 minutes were examined in terms of colony reduction. Result and Discussion: As a result of the efficacy tests, NpAg solution showed a 46.67% (0.27 log) decrease in E. faecalis concentration and a 58.8% (0.38 log) decrease in S. mutans concentration. Similarly, H2O8 solution showed an 84.67% (0.81 log) decrease in E. faecalis concentration and a 62.94% (0.43 log) decrease in S. mutans concentration. Under the limitations of this study, it was concluded that super anionic oxygen solutions (NpAg) and super anionic oxygen solutions (H2O8) have a significant antimicrobial flora against E. faecalis and S. mutans, but are attenuated when compared to irrigants routinely used clinically. Since this study did not simulate the oral environment, future studies may provide more effective results.