A selective sensor based on Au nanoparticles-graphene oxide-poly(2,6-pyridinedicarboxylic acid) composite for simultaneous electrochemical determination of ascorbic acid, dopamine, and uric acid

AYDOĞDU TIĞ G., Gunendi G., Pekyardimci S.

JOURNAL OF APPLIED ELECTROCHEMISTRY, cilt.47, sa.5, ss.607-618, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s10800-017-1060-7
  • Dergi Adı: JOURNAL OF APPLIED ELECTROCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.607-618
  • Anahtar Kelimeler: Poly(2,6-pyridinedicarboxylic acid), Graphene oxide, Simultaneous determination, Ascorbic acid, Dopamine, Uric acid, GLASSY-CARBON ELECTRODE, FILM-MODIFIED ELECTRODE, OXIDE DOPED POLY(3,4-ETHYLENEDIOXYTHIOPHENE), GOLD NANOPARTICLES, NANOTUBE, FACILE, HYPOXANTHINE, XANTHINE, PLATFORM, POLYMER
  • Ankara Üniversitesi Adresli: Evet

Özet

A new strategy based on gold nanoparticles (AuNPs), poly(2,6-pyridinedicarboxylic acid) (P(PDA)), and a graphene oxide (GO)-modified glassy carbon electrode (GCE/AuNPs/P(PDA)-GO) for the simultaneous electrochemical determination of ascorbic acid (AA), dopamine (DA), and uric acid (UA) was proposed in this study. The composite electrode was characterized using scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV). The GCE/AuNPs/P(PDA)/GO exhibited good electrochemical behavior towards the electrocatalysis of AA, DA, and UA due to the synergistic effects between P(PDA), GO, and AuNPs. The electro-oxidation signals appeared as three clearly seperated peaks with remarkable peak potential differences of 0.161 V (AA-DA), 0.336 V (AA-UA), and 0.175 V (DA-UA). The linear responses of AA, DA, and UA were in the concentration ranges of 6.0 to 2400.0, 0.05 to 100.0, and 0.5 to 150.0 A mu mol L-aEuro'1 with the detection limits of 1.764, 0.017, and 0.160 A mu mol L-aEuro'1, respectively. The sensor was used for the voltammetric determination of AA, DA, and UA in human urine samples using the standard addition method with satisfactory results.