Akademik Veri Yönetim Sistemi
Microchemical Journal, cilt.224, 2026 (SCI-Expanded, Scopus)
Isocycloseram (ISO) is an isoxazoline insecticide, efficiently controlling the diamondback moth in crops. In this work, a new molecularly imprinted quartz crystal microbalance (QCM) sensor was developed for ISO detection in orange juice samples. For this aim, a sulphur doped magnesium oxide (MgO) nanocomposite (S-MgO NanoCom) was first prepared by using annealing treatment and QCM chips based on S-MgO NanoCom was developed by an interaction between gold surface of QCM chip and sulphur element of the nanocomposite. Then, a molecularly imprinted QCM sensor with S-MgO nanocomposite was fabricated using UV polymerization, incorporating methacryloylamidoglutamic acid (MAGA) as the monomer and N,N′-azobisisobutyronitrile (AIBN) as the initiator and it demonstrated a range of linearity from 1.0 × 10−9 to 1.0 × 10−8 mol L−1, achieving a detection limit (LOD) of 3.30 × 10−10 mol L−1. In addition, the developed QCM sensor was successfully applied to orange juice samples, demonstrating high recovery rates. Finally, the comprehensive examinations were conducted to assess the stability, selectivity, repeatability, reproducibility, ruggedness, and robustness of the developed QCM sensor in detail.