Off-label use of alitretinoin Alitretinoin und Off-label-Use

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Fritz K., Tiplica G., Salavastru C., Onder M.

Hautarzt, vol.64, no.10, pp.748-751, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 64 Issue: 10
  • Publication Date: 2013
  • Doi Number: 10.1007/s00105-013-2593-2
  • Journal Name: Hautarzt
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.748-751
  • Keywords: Hand eczema, Retinoid, Side effects, Vitamin A acid receptors, Vitamin A derivative
  • Ankara University Affiliated: No

Abstract

Oral alitretinoin (9-cis retinoic acid) is an endogenous retinoid related to vitamin A. Studies have shown that oral alitretinoin is effective and well-tolerated in the treatment of severe chronic hand eczema, so that it is approved for this indication. This review summarizes new studies and clinical experience on the off-label use of alitretinoin. © 2013 Springer-Verlag Berlin Heidelberg.