SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NOVEL SULFONYLAMIDO-BENZOXAZOLES

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ARPACI Ö., Doganc F., Sac D., Sari E., KAYNAK ONURDAĞ F., ÖKTEN S.

ACTA BIOLOGICA HUNGARICA, cilt.67, sa.1, ss.75-84, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1556/018.67.2016.1.6
  • Dergi Adı: ACTA BIOLOGICA HUNGARICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.75-84
  • Anahtar Kelimeler: Benzoxazole, sulfonylamides, antibacterial activity, antifungal activity, synthesis, ANALOGS
  • Ankara Üniversitesi Adresli: Evet

Özet

A series of 2-(p-substituted phenyl)-5-[(4-substituted phenyl) sulfonylamido]-benzoxazoles were synthesized and tested for their antimicrobial activities. The structures of the new derivatives were elucidated by spectral techniques. The minimum inhibitory concentrations (MIC) of the new benzoxazoles were determined against standard bacterial and fungal strains and drug-resistant isolates and compared to those of several reference drugs.