The characteristics of anti-neutrophyl cytoplasmic antibodies in inflammatory bowel disease Inflamatuvar barsak hastaliklarinda anti-notrofilik sitoplazmik antikorun ozellikleri

Tezel A., Dagli U., Hamzaoglu H., DALVA K., Baysal C., Serin A., ...Daha Fazla

Turkish Journal of Gastroenterology, cilt.8, sa.4, ss.434-439, 1997 (Scopus, TRDizin) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 4
  • Basım Tarihi: 1997
  • Dergi Adı: Turkish Journal of Gastroenterology
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.434-439
  • Anahtar Kelimeler: ANCA, Crohn's disease, Inflammatory bowel disease, Ulcerative colitis
  • Ankara Üniversitesi Adresli: Evet

Özet

Anti-neutrophil cytoplasmic antibodies (ANCA) were found positive in 29 of 46 (63%) ulcerative colitis (UC) patients and in 3 of 13 (13%) Crohn's Disease (CD) patients whereas non of the controls were found ANCA positive. The differences were statistical positive in both groups when compared with control group (p<0.0001). Among 29 ANCA positive UC patients 22 (75%) patients had positive p-ANCA and 7 (25%) had positive c-ANCA. All three of ANCA positive CD patients showed p-ANCA pattern. No correlation were found between activity, localisation, duration and the management of UC and ANCA positivity (p=0.06, p=0.36, p=0.59, p=0.84 respectively). One of the p-ANCA positive UC patients had anti MPO antibody against myeloperoxidase.