Remission criteria for the follow-up of patients with acromegaly

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Gullu S., Keles H., Delibasi T., Tonyukuk V., Kamel N., Erdogan G.

EUROPEAN JOURNAL OF ENDOCRINOLOGY, vol.150, no.4, pp.465-471, 2004 (SCI-Expanded, Scopus)

• Publication Type: Article / Article
• Volume: 150 Issue: 4
• Publication Date: 2004
• Doi Number: 10.1530/eje.0.1500465
• Journal Name: EUROPEAN JOURNAL OF ENDOCRINOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.465-471
• Open Archive Collection: AVESIS Open Access Collection
• Ankara University Affiliated: No

Abstract

Objective: The aim was to evaluate the validity of current remission criteria in acromegaly. a random GH level of < 2.5 mug/l, a glucose-suppressed GH level of < 1 mug/l and a normal IGF-I level. Design: In forty-one patients treated for acromegaly (23 males and 18 females, 20 - 69 years) and 94 healthy subjects (50 males and 44 females, 20-78 years), basal GH and IGF-I levels and nadir GH levels after 75 g oral glucose were evaluated in decade blocks; these were assayed by sensitive immunoradiometric assays.