Experimental Chronic Toxoplasmosis Model in Mice: Brain Lesions and Related Behavioral Changes

KOÇAK O. M., Atmaca H. T., TERZİ O. S., Buyukkayaer S., Ozdemir H., Uzunalioglu T., ...Daha Fazla

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.49, sa.2, ss.139-144, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.4274/npa.y6302
  • Dergi Adı: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.139-144
  • Anahtar Kelimeler: Toxoplasma gondii, mice, tissue cyst, behavior, ELEVATED PLUS-MAZE, TRAFFIC ACCIDENTS, GONDII INFECTION, HOST BEHAVIOR, ANXIETY, RISK, RATS, ASTROCYTES, DISORDERS, AMYGDALA
  • Ankara Üniversitesi Adresli: Hayır

Özet

Objective: In this study, it is aimed to constitute a chronic toxoplasmosis model using toxoplasma gondii (T. gondii) ME49 strain that is supposed to produce tissue cysts, to compare healthy and infected mice in terms of behavioral changes. In addition, the relationship between behavioral changes and brain lesions was questioned.