Imaging of Hypoxia in Liver Tumors With 18F-FMISO PET Before Selective Internal Radiotherapy With 90Y Microspheres.

SOYDAL Ç., DEMİR B., DURSUN E., Sutcu G., ÇELEBİOĞLU E. C., Sadik Bilgic M., ...Daha Fazla

Clinical nuclear medicine, cilt.49, sa.11, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 11
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1097/rlu.0000000000005323
  • Dergi Adı: Clinical nuclear medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Anahtar Kelimeler: 18F-FDG, carcinoma, hepatocellular, misonidazole, MRI, PET
  • Ankara Üniversitesi Adresli: Evet

Özet

Hypoxia is a known cause of resistance to radiotherapy and chemotherapy. Although there are multiple studies in external radiation therapies based on hypoxia PET, the effect of hypoxia in radioembolization is largely unknown. Here we present 2 cases of hepatocellular carcinoma patients from a prospective study with different lesion characteristics on pretreatment 18F-FMISO PET and varying responses on 18F-FDG PET.