Imaging of Hypoxia in Liver Tumors With 18F-FMISO PET Before Selective Internal Radiotherapy With 90Y Microspheres.

SOYDAL Ç., DEMİR B., DURSUN E., Sutcu G., ÇELEBİOĞLU E. C., Sadik Bilgic M., ...More

Clinical nuclear medicine, vol.49, no.11, 2024 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 11
  • Publication Date: 2024
  • Doi Number: 10.1097/rlu.0000000000005323
  • Journal Name: Clinical nuclear medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Keywords: 18F-FDG, carcinoma, hepatocellular, misonidazole, MRI, PET
  • Ankara University Affiliated: Yes

Abstract

Hypoxia is a known cause of resistance to radiotherapy and chemotherapy. Although there are multiple studies in external radiation therapies based on hypoxia PET, the effect of hypoxia in radioembolization is largely unknown. Here we present 2 cases of hepatocellular carcinoma patients from a prospective study with different lesion characteristics on pretreatment 18F-FMISO PET and varying responses on 18F-FDG PET.