Clinical Management of Patients with a History of Urticaria/Angioedema Induced by Multiple NSAIDs: An Expert Panel Review

Asero R., BAVBEK S., Blanca M., Blanca-Lopez N., Cortellini G., Nizankowska-Mogilnicka E., ...More

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, vol.160, no.2, pp.126-133, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 160 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1159/000342424
  • Journal Name: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.126-133
  • Keywords: NSAID, Urticaria, Cross-reactivity, Oral challenge tests, COX-1, COX-2, Nonsteroidal anti-inflammatory drug hypersensitivity, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, ASPIRIN-INDUCED URTICARIA, INDUCED SKIN DISORDERS, ADVERSE-REACTIONS, CYCLOOXYGENASE-2 INHIBITORS, TERM TOLERABILITY, RISK-FACTORS, INTOLERANCE, HYPERSENSITIVITY, ETORICOXIB
  • Ankara University Affiliated: Yes

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most frequent causes of drug-induced urticaria/angioedema worldwide. Recent review articles have classified patients experiencing NSAID-induced urticaria/angioedema into different categories, including single reactors, multiple reactors, and multiple reactors with underlying chronic urticaria. Each of these categories requires a different clinical approach. The present article, written by a panel of experts, reports the main recommendations for the practical clinical management of patients with a history of urticaria/angioedema induced by multiple NSAID based on current knowledge. Copyright (c) 2012 S. Karger AG, Basel