Neutrophil volume, conductivity and scatter parameters with effective modeling of molecular activity statistical program gives better results in neonatal sepsis

Celik I. H., Demirel G., Sukhachev D., Erdeve Ö., Dilmen U.

INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, cilt.35, sa.1, ss.82-87, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1111/ijlh.12002
  • Dergi Adı: INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.82-87
  • Anahtar Kelimeler: Neutrophil volume, conductivity and scatter parameters, effective modeling of molecular activity statistical program, neonatal sepsis, C-REACTIVE PROTEIN, AUTOMATED-DETERMINATION, BACTERIAL-INFECTIONS, VCS PARAMETERS, INTERLEUKIN-6, DIAGNOSIS, INDICATORS, PREDICTION
  • Ankara Üniversitesi Adresli: Evet

Özet

Introduction: Neonatal sepsis remains an important clinical syndrome despite advances in neonatology. Current hematology analyzers can determine cell volume (V), conductivity for internal composition of cell (C) and light scatter for cytoplasmic granularity and nuclear structure (S), and standard deviations which are effective in the diagnosis of sepsis. Statistical models can be used to strengthen the diagnosis. Effective modeling of molecular activity (EMMA) uses combinatorial algorithm of the selection parameters for regression equation based on modified stepwise procedure. It allows obtaining different regression models with different combinations of parameters.