Quantification of shikimic acid in the methanolic extracts of three Alnus taxons growing in Turkey Türkiye’de yetişen üç Alnus taksonunun metanollü ekstrelerinde şikimik asit miktar tayini

Altinyay Ç., ERGENE B., ALTUN M. L.

Turkish Journal of Pharmaceutical Sciences, cilt.13, sa.1, ss.115-120, 2016 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5505/tjps.2016.29591
  • Dergi Adı: Turkish Journal of Pharmaceutical Sciences
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.115-120
  • Anahtar Kelimeler: Alnus, Betulaceae, HPLC, Quantitative analysis, Shikimic acid
  • Ankara Üniversitesi Adresli: Evet

Özet

© 2016, Turkish Pharmacists Association. All rights reserved.Shikimic acid is a phenolic acid which is known to possess several activities and it takes attention as a leading compound to some synthetic medicinal substances as well. In this study, high performance liquid chromatographic analyses were carried out in order to determine shikimic acid contents of Alnus glutinosa subsp. glutinosa, A. orientalis var. orientalis and A. orientalis var. pubescens; acetonitrile and 0.2% o-phosphoric acid:water mixture with isocratic flow was used as mobile phase. The flow rate was 0.5 ml/min. The quantitative analysis of methanol extracts prepared from the leaves of A. glutinosa subsp. glutinosa, A. orientalis var. orientalis and A. orientalis var. pubescens revealed that shikimic acid amount was found to be 0.6491%, 0.4309% and 0.2452% respectively.