Prolonged Tracheal Intubation and the Association Between Patent Ductus Arteriosus and Bronchopulmonary Dysplasia: A Secondary Analysis of the PDA-TOLERATE trial

Clyman R. I., Kaempf J., Liebowitz M., ERDEVE Ö., Bulbul A., Hakansson S., ...More

JOURNAL OF PEDIATRICS, vol.229, pp.283-290, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 229
  • Publication Date: 2021
  • Doi Number: 10.1016/j.jpeds.2020.09.047
  • Journal Name: JOURNAL OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.283-290
  • Ankara University Affiliated: Yes

Abstract

In the PDA-TOLERATE trial, persistent (even for several weeks) moderate to large patent ductus arteriosus (PDA) was not associated with an increased risk of BPD when the infant required <10 days of intubation. However, in infants requiring intubation for >= 10 days, prolonged PDA exposure (>= 11 days) was associated with an increased risk of moderate/severe BPD.