Statin pretreatment and risk of in-hospital atrial fibrillation among patients undergoing cardiac surgery: a collaborative meta-analysis of 11 randomized controlled trials

Patti, Giuseppe; Bennett, Rachel; Seshasai, Sreenivasa; Cannon, Christopher; Cavallari, Ilaria; Chello, Massimo; Nusca, Annunziata; Mega, Simona; Caorsi, Carlos; Spadaccio, Cristiano; On, Young; Mannacio, Vito; Berkan, Ocal; YILMAZ, MEHMET; Katrancioglu, Nurkay; Ji, Qiang; Kourliouros, Antonios; BARAN, ÇAĞDAŞ; Pasceri, Vincenzo; AKAR, AHMET; Kaski, Juan; Di Sciascio, Germano; Ray, Kausik

doi:10.1093/europace/euv001

Statin pretreatment and risk of in-hospital atrial fibrillation among patients undergoing cardiac surgery: a collaborative meta-analysis of 11 randomized controlled trials

Atıf İçin Kopyala

Patti G., Bennett R., Seshasai S. R. K., Cannon C. P., Cavallari I., Chello M., ...Daha Fazla

EUROPACE, cilt.17, sa.6, ss.855-863, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 17 Sayı: 6
Basım Tarihi: 2015
Doi Numarası: 10.1093/europace/euv001
Dergi Adı: EUROPACE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.855-863
Anahtar Kelimeler: Statins, Cardiac surgery, Postoperative atrial fibrillation, Meta-analysis, ENDOTHELIAL PROGENITOR CELLS, PREOPERATIVE STATINS, UPSTREAM THERAPIES, CLINICAL-EVIDENCE, CORONARY SURGERY, EUROPEAN-SOCIETY, BYPASS-SURGERY, DOUBLE-BLIND, TROPONIN-I, ATORVASTATIN
Ankara Üniversitesi Adresli: Evet

Özet

Aims Statin pretreatment in patients undergoing cardiac surgery is understood to prevent postoperative atrial fibrillation (AF). However, this is based on observational and limited randomized trial evidence, resulting in uncertainty about any genuine anti-arrhythmic benefits of these agents in this setting. We therefore aimed to quantify precisely the association between statin pretreatment and postoperative AF among patients undergoing cardiac surgery.