Does dipyrone have any effect on respiratory function in COPD patients?

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Gulmez S., Tulunay F., Beder S., KAYACAN O., Karnak D.

RESPIRATORY MEDICINE, cilt.100, sa.5, ss.828-834, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 100 Sayı: 5
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.rmed.2005.09.002
  • Dergi Adı: RESPIRATORY MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.828-834
  • Anahtar Kelimeler: dipyrone (metamizole), chronic obstructive pulmonary disease (COPD), bronchodilation, spirometry
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Dipyrone (Novalgin((R))) is an effective analgesic, antipyretic agent also with spasmolytic effects on various types of smooth muscles. It has recently been reported that dipyrone relaxes tracheal smooth muscle of guinea pig. In this present study, we aimed to investigate whether this and previously reported in vitro results have any consequences on the respiratory function of normal healthy volunteers and chronic obstructive pulmonary disease (COPD) patients.