Improvement of left ventricular function and wall motion abnormalities after recanalization of total occlusion of left anterior descending coronary artery by percutaneous transluminal coronary angioplasty

Pamir G., Oral D., Omurlu K., Erol Ç., Kervancioglu C., Akgun G., ...More

JOURNAL OF INVASIVE CARDIOLOGY, vol.9, no.6, pp.417-423, 1997 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 6
  • Publication Date: 1997
  • Journal Name: JOURNAL OF INVASIVE CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.417-423
  • Keywords: hibernating myocardium, aneurysm, coronary balloon angioplasty, coronary occlusions, MYOCARDIAL-INFARCTION, BALLOON ANGIOPLASTY, FOLLOW-UP, DISEASE, REVASCULARIZATION, STENOSES, ANEURYSM, SUCCESS
  • Ankara University Affiliated: Yes

Abstract

PTCA was performed in 262 consecutive patients (pts) with total LAD occlusion. TIMI 3 flow was established in 164 pts (success rate was 62.6%). After 4-6 months a follow-up angiography of 72 pts showed restenosis in 39 pts (restenosis rate was 54.2%). In 33 pts without restenosis there was a significant increase in ejection fraction (EF) (54.6 +/- 15 versus 59.8 +/- 18.1 before and after PTCA respectively, p = 0.02). Improvement of wall motion abnormalities (WMA) in 12 of 26 pts was observed. Anterolateral-apical (AL-A) aneurysm disappeared in 6 pts and limited to apex in 2 pts. AL-A hypokinesia in 3 and akinesia in 1 reversed to normal wall motion (NWM). There was not a significant change in EF in either of the groups of pts with reocclusion (24 pts) or restenosis (15 pts) (p > 0.05). However, AL-A aneurysm disappeared in 2 of 12 pts with WMA before PTCA although there was restenosis (but TIMI 3 flow) on follow-up coronary angiogram. In 3 pts with restenosis but not reocclusion AL-A hypokinesia, akinesia and apical dyskinesia returned to NWM. No significant changes were observed in the left ventricular end diastolic pressures (LVEDP) in both pt groups with or without improvement of WMA (p > 0.05). Filling fractions (FF) did not change in patients with or without restenosis.