JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES, cilt.28, sa.6, ss.645-649, 2018 (SCI-Expanded)
Objective: To compare the perioperative outcomes of patients with uterine cancer, who were operated using advanced or conventional bipolar instruments. Materials and Methods: Patients with clinically early-stage endometrial cancer were randomized to advanced (LigaSure) or conventional (Robi forceps) bipolar groups. Surgeries were performed by laparoscopy. Hysterectomy and bilateral salpingo-oophorectomy with retroperitoneal lymphadenectomy were done in all cases. Primary endpoint of the study was to compare operation time for 2 groups. Other perioperative outcomes were also compared. ClinicalTrials.gov identifier number of the study was NCT02822820. Results: Sixty-eight cases with endometrial cancer were randomized to 2 groups and each group included 34 subjects. Mean age and body mass index of all cases were 56.810.4 years and 31.1 +/- 5.3kg/m(2), respectively. Mean operation time was found significantly shorter in advanced bipolar group (134.2 +/- 29.7 minutes versus 163.5 +/- 27.7 minutes, P<.001). The other variables investigated such as intraoperative blood loss, duration of hospital stay, and postoperative pain scores did not show statistically significant difference between the groups. Conclusion: Operation time was shorter in advanced bipolar group, however, advanced and conventional bipolar energy instruments were comparable for other perioperative outcomes in laparoscopic endometrial cancer surgery.