P53 codon 213 (a-g) polymorphism in a turkish population


Ilhan I., Erekul S., Ateşalp S., İLHAN O., Akar N.

Pediatric Hematology and Oncology, cilt.12, sa.5, ss.499-501, 1995 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 5
  • Basım Tarihi: 1995
  • Doi Numarası: 10.3109/08880019509009482
  • Dergi Adı: Pediatric Hematology and Oncology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.499-501
  • Anahtar Kelimeler: Malignancy, P53
  • Ankara Üniversitesi Adresli: Evet

Özet

We studied a rare polymorphism at exon 6 (CD 213) of the p53 gene in a healthy Turkish population (n == 26) and in Turks with different types of tumors such as malignant lymphoma (n == 12), osteosarcoma (n == 5), and nasopharyngeal sarcoma (n == 4). The polymorphic allele was found in only one of the malignant lymphoma patients (4.16% Our data revealed that CD 213 (A-G) polymorphism is very rare in the Turkish population and there is no association with the tumors. © 1995 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.