Role of neutrophil-to-lymphocyte ratio in prediction of Gleason score upgrading and disease upstaging in low-risk prostate cancer patients eligible for active surveillance

GÖKCE, MEHMET; Tangal, Semih; Hamidi, Nurullah; SÜER, EVREN; Ibis, MUHAMMED; Beduk, Yasar

doi:10.5489/cuaj.3550

Role of neutrophil-to-lymphocyte ratio in prediction of Gleason score upgrading and disease upstaging in low-risk prostate cancer patients eligible for active surveillance

GÖKCE M. İ., Tangal S., Hamidi N., SÜER E., Ibis M. A., Beduk Y.

CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL, cilt.10, sa.11-12, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 10 Sayı: 11-12
Basım Tarihi: 2016
Doi Numarası: 10.5489/cuaj.3550
Dergi Adı: CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Ankara Üniversitesi Adresli: Evet

Özet

Introduction: Active surveillance (AS) is an option for management of low-risk prostate cancer (PCa). However, grade and stage progression is an important consideration. Neutrophil-to-lymphocyte ratio (NLR) is a useful marker of cancer-related inflammation. In this study, we aimed to identify the roles of neutrophil count (NC), lymphocyte count (LC), and NLR to predict Gleason score (GS) upgrading, disease upstaging, and biochemical recurrence rates (BCR) in low-risk PCa patients.