BCL-2 PROTEIN IN NON-SMALL-CELL LUNG-CARCINOMA

PEZZELLA F., TURLEY H., KUZU I., TUNGEKAR M., DUNNILL M., PIERCE C., ...Daha Fazla

NEW ENGLAND JOURNAL OF MEDICINE, cilt.329, sa.10, ss.690-694, 1993 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 329 Sayı: 10
  • Basım Tarihi: 1993
  • Doi Numarası: 10.1056/nejm199309023291003
  • Dergi Adı: NEW ENGLAND JOURNAL OF MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.690-694
  • Ankara Üniversitesi Adresli: Hayır

Özet

Background. The proto-oncogene bcl-2 encodes a protein that inhibits programmed cell death (apoptosis). The protein is expressed in basal cells in normal human epithelium, but no data are available on the frequency or clinical importance of its expression in carcinoma. We studied bcl-2 expression in patients with non-small-cell lung carcinoma and correlated this phenomenon with survival.