Association of HLA-B27, MEFV gene mutations, ERAP1, IL12B and IL23R gene polymorphisms with ankylosing spondylitis

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Pekacar F. S., AKDOĞAN A., HAYRAN K. M., ÇOLAK R., Yilmaz E.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.39, sa.4, ss.482-487, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5505/tjb.2014.44265
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.482-487
  • Anahtar Kelimeler: Ankylosing spondylitis, HLA-B27, MEFV, ERAP1, IL12B and IL23R, FAMILIAL MEDITERRANEAN FEVER, GENOME-WIDE ASSOCIATION, DISEASE SEVERITY, SUSCEPTIBILITY, PREVALENCE, FREQUENCY, RISK, TURKEY
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Genetic factors have an important role in the pathogenesis of ankylosing spondylitis (AS). The aim of this study was to analyse the association of HLA-B27, MEFV mutations, IL12B, IL23R and ERAP1 polymorphisms in Turkish patients with ankylosing spondylitis.