Duodenogastric gadoxetic acid reflux and upper endoscopy findings


KUL M., KURU ÖZ D., AVCI O., ERDEN G. A.

European Congress of Radiology, Viyana, Avusturya, 13 - 17 Temmuz 2022

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Doi Numarası: 10.26044/ecr2022/c-15397
  • Basıldığı Şehir: Viyana
  • Basıldığı Ülke: Avusturya
  • Ankara Üniversitesi Adresli: Evet

Özet

ile reflux is defined as the duodenogastric backflow of alkaline duodenopancreatic secretions including bile salts (1). Bile reflux occuring postprandially or in the early morning hours is physiologic. However, after gallbladder removal, gastric surgery, or due to pyloric sphincter dysfunction bile reflux might be excessive, frequent and longer in duration and, thus, is considered as pathologic.  (2-5).

This condition may cause chemical gastropathy/gastritis owing to the chemical irritation of the gastric mucosa and might raise the risk of gastric malignancy (6, 7).

In the clinical routine, diagnosis of bile reflux is made via upper endoscopy. However, a recent study revealed a lower accuracy and predictive value of upper endoscopy  compared to gastric pH monitoring and hepatobiliary scintigraphy in terms of bile reflux diagnosis (8). Since histopathologic findings of reflux gastritis are indistinguishable from other causes of chemical gastrtitis, detection of gastric bile stain is of particular importance for an adequate diagnosis.

Gadoxetic acid, a hepatocyte-specific contrast agent routinely used in hepatobiliary MR imaging, is expected to be seen in the biliary tree and duodenum 15-20 minutes after intravenous injection (9).

In this study, we aimed to emphasize that duodenal contrast reflux into the stomach might occur during routine gadoxetic-acid enhanced hepatic MRI, and, in addition, to correlate this finding with upper gastrointestinal endoscopy results.