HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?


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ZIROĞLU Z., SORGUN M. H., TABAN E. F., AYDEMİR S. T., LEVENT H. Ç., ULUKAN Ç., ...Daha Fazla

Türk Beyin Damar Hastalıkları Dergisi, cilt.27, sa.3, ss.191-199, 2021 (Hakemli Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5505/tbdhd.2021.23590
  • Dergi Adı: Türk Beyin Damar Hastalıkları Dergisi
  • Derginin Tarandığı İndeksler: EMBASE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.191-199
  • Ankara Üniversitesi Adresli: Evet

Özet

INTRODUCTION: Many studies are examining the relationship between cardiovascular diseases and triglyceride levels, and it has been shown that hypertriglyceridemia significantly increases the risk independently. In this study, we wanted to investigate whether there is a similar relationship for stroke. METHODS: A total of 619 patients hospitalized with a diagnosis of acute ischemic stroke in our stroke center were included in the study. Demographic information, accompanying risk factors, hemoglobin level, thrombocyte count, triglyceride level, and C reactive protein level at the time of admission, and the National Institutes of Health Stroke Scale (NIHSS) scores in the first evaluation were recorded. Also, information about mortality in hospital, recurrent stroke, and the modified Rankin Scale (mRS) scores in the follow-up period was entered in our local database. RESULTS: While 182 patients (32.3%) (78 females (42.9%) and 104 males (57.1%); mean age 64.5±12.01 years) were diagnosed with hypertriglyceridemia, this number was 25 (4.4%) patients (13 females (52%) and 12 males (48%); mean age 70.9±17.4 years) for hypotriglyceridemia. Among the risk factors studied, only diabetes mellitus was found to be associated with hypertriglyceridemia in patients with acute ischemic stroke (P<0.05). DISCUSSION AND CONCLUSION: In this study conducted in our stroke center, hypertriglyceridemia and hypotriglyceridemia prevalences were found as 32.3% and 4.4%, respectively. HyperTG or hypoTG did not significantly affect on stroke severity and prognosis. We found out that DM is the major risk factor for acute ischemic stroke patients with hyperTG.