Corneal Melanoma: Report of Three Cases

Uçakhan-Gündüz Ö. Ö., GÜNDÜZ K., Karsloǧlu M. Z., Okçu-Heper A., Kanpolat A. K.

EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE, sa.5, ss.341-344, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1097/icl.0b013e318237d195
  • Dergi Adı: EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.341-344
  • Anahtar Kelimeler: Corneal melanoma, Conjunctival melanoma, Keratectomy, mitomycin-C
  • Ankara Üniversitesi Adresli: Evet

Özet

Objectives: We report three cases of corneal melanoma: two without conjunctival primary acquired melanosis or melanoma and one with a history of conjunctival melanoma. Methods: Report of 3 cases with corneal melanoma and literature review. Results: Medical records of three patients with the diagnosis of corneal melanoma were reviewed. Total excisional biopsy with corneal epitheliectomy using 20% ethanol was performed. Postoperative topical chemotherapy with 0.04% mitomycin-C was used for 4 weeks as adjunctive therapy. The follow-up ranged from 13 months to 7 years. Each of the two patients experienced two recurrences. One was treated in a fashion similar to that of the initial tumor, and the other was treated by enucleation. None of the patients developed regional or distant metastasis. Conclusions: Malignant melanoma can rarely occur on the cornea with no contiguous conjunctival component. Eye-conserving treatment should be attempted first. Recurrences may occur, and a close follow-up is necessary.