Pathomorphological and immunohistochemical findings in a case of extragenital canine transmissible venereal tumour


Coskan A., Alcigir M., VURAL S.

Bulgarian Journal of Veterinary Medicine, cilt.14, sa.4, ss.252-256, 2011 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 4
  • Basım Tarihi: 2011
  • Dergi Adı: Bulgarian Journal of Veterinary Medicine
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.252-256
  • Anahtar Kelimeler: Canine transmissible venereal tumour, Immunohistochemistry, Nasal sinus, Pathomorphology
  • Ankara Üniversitesi Adresli: Evet

Özet

An extragenital canine transmissible venereal tumour was described pathomorphologically and immunohistochemically in the nasal sinus of a 7-year-old female German Shepherd dog. The tumour removed from the nasal sinus weighed 45 g and was multilobullary, firm in consistency, with grayishwhite colour. Histopathologically, ovoid- or round-shaped neoplastic cells with prominent, clear, large, round to ovoid hyperchromatic nuclei were seen. In general the cells were with a less dense distinct cytoplasm, solid or in cords. Immunohistochemically, positive reactions in tumour cells were detected by p53 protein, vimentin and α1 chymotrypsin antibodies.