A CASE OF FETAL CARBAMAZEPINE SYNDROME WITH RIGHT HEMIHYPOPLASIA OF THE ENTIRE BODY

Akar M., Dilli D., Yilmaz Y., Erdeve Ö., Oguz S., Uras N., ...Daha Fazla

GENETIC COUNSELING, cilt.23, sa.1, ss.19-24, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 1
  • Basım Tarihi: 2012
  • Dergi Adı: GENETIC COUNSELING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.19-24
  • Anahtar Kelimeler: Maternal epilepsy, Fetal carbamazepine syndrome, Hemihypoplasia, Teratogenicity, Pregnancy, CONGENITAL-MALFORMATIONS, PREGNANCY, MONOTHERAPY, WOMEN
  • Ankara Üniversitesi Adresli: Evet

Özet

A case of fetal carbamazepine syndrome with right hemihypoplasia of the entire body: Anticonvulsant drugs taken by pregnant women to prevent seizures are among the most common causes of potential harm to the fetus. It has been suggested that carbamazepine was less teratogenic than the other drugs. Here, we report a case of fetal carbamazepine syndrome presenting with facial dysmorphism, congenital heart defect, skeletal abnormalities, renal agenesis, ambiguous genitalia, anal atresia, and right hemihypoplasia of the entire body. To the best of our knowledge this is the most severe case of fetal carbamazepine syndrome in the literature. This case can provide useful data about teratogenicity of carbamazepine therapy during the pregnancy.