A sensitive voltammetric sensor for specific recognition of vitamin C in human plasma based on MAPbl(3) perovskite nanorods

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TIRIS G., Khoshnavaz Y., Oven E. N., Mehmandoust M., ERK N.

JOURNAL OF ELECTROCHEMICAL SCIENCE AND ENGINEERING, cilt.12, ss.175-183, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5599/jese.1153
  • Dergi Adı: JOURNAL OF ELECTROCHEMICAL SCIENCE AND ENGINEERING
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.175-183
  • Anahtar Kelimeler: Voltammetry, ascorbic acid, MAPbl(3), cysteine, human plasma, CARBON-PASTE ELECTRODE, ASCORBIC-ACID, ELECTROCATALYTIC DETERMINATION, ELECTROCHEMICAL SENSOR, HYBRID, PHASE
  • Ankara Üniversitesi Adresli: Evet

Özet

A novel and sensitive electrode was suggested for the rapid determination of ascorbic acid (AA) using a glassy carbon electrode (GCE) modified with synthesized MAPbl(3) and L-cys (L-cys/MAPbl(3)/GCE). Determination of ascorbic acid as an important component of the human diet due to help in decreasing blood pressure and improving endothelial function is crucial. The synthesized MAPbl(3) was characterized by different methods, including transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD). The fabricated electrode exhibited superior electrical conductivity and fast electron transfer kinetics. The results illustrated that the developed electrode had an outstanding electrocatalytic activity towards the oxidation of AA in 0.1 M Britton-Robinson buffer(B-R) as a supporting electrolyte. The modified electrode demonstrated a linear range in differential pulse voltammetry of 0.02-11.4 mu M with a low detection limit of 8.0 nM for ascorbic acid. It can be stated that the proposed sensor can be successfully applied to the determination of ascorbic acid in human plasma samples.