Coupling of a P2Z-like purinoceptor to a fatty acid-activated K+ channel in toad gastric smooth muscle cells

Zou, H; Ugur, MEHMET; Drummond, RM; Singer, JJ

doi:10.1111/j.1469-7793.2001.00059.x

Coupling of a P2Z-like purinoceptor to a fatty acid-activated K+ channel in toad gastric smooth muscle cells

Zou H., Ugur M., Drummond R., Singer J.

JOURNAL OF PHYSIOLOGY-LONDON, cilt.534, sa.1, ss.59-70, 2001 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 534 Sayı: 1
Basım Tarihi: 2001
Doi Numarası: 10.1111/j.1469-7793.2001.00059.x
Dergi Adı: JOURNAL OF PHYSIOLOGY-LONDON
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.59-70
Ankara Üniversitesi Adresli: Evet

Özet

1. Extracellular application of ATP generates two whole-cell currents in toad gastric smooth muscle cells: an immediate inward non-selective cation current (due to the activation of a P2X or P2Z-like receptor) and a slowly developing outward K+ current. The inward non-selective cation current depends on the continuous presence of ATP while the outward K+ current can last for minutes after ATP application ceases.