Flow cytometric DNA analysis, and immunohistochemical p53, PCNA and histopathologic study in primary achalasia: Preliminary results

Bektas A., Yasa M., KUZU I., Dogan I., ÜNAL S., Ormeci N.

HEPATO-GASTROENTEROLOGY, cilt.48, sa.38, ss.408-412, 2001 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 38
  • Basım Tarihi: 2001
  • Dergi Adı: HEPATO-GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.408-412
  • Anahtar Kelimeler: primary achalasia, DNA ploidy, proliferating cell, nuclear antigen (PCNA), p53, CELL NUCLEAR ANTIGEN, TUMOR-SUPPRESSOR GENE, ESOPHAGEAL PRECANCEROUS LESIONS, BARRETTS-ESOPHAGUS, EPITHELIAL DYSPLASIA, CARCINOMA, HETEROGENEITY, REPLICATION, PROGRESSION, MALIGNANCY
  • Ankara Üniversitesi Adresli: Hayır

Özet

Background/Aims: Primary achalasia Is a premalignant disorder of the esophagus. The studies for esophageal cancer pathogenesis may reveal early diagnosis of esophageal cancer. DNA aneuploidy, p53 mutations and cellular proliferation are important factors in cancer development. As far as we know, we have not encountered any study on these factors in achalasia.