Atıf İçin Kopyala
ENGİN A. B., ENGİN E. D.
TURKISH JOURNAL OF IMMUNOLOGY, cilt.7, sa.1, ss.40-49, 2019 (ESCI)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
7
Sayı:
1
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Basım Tarihi:
2019
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Doi Numarası:
10.25002/tji.2019.1037
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Dergi Adı:
TURKISH JOURNAL OF IMMUNOLOGY
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Derginin Tarandığı İndeksler:
Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
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Sayfa Sayıları:
ss.40-49
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Anahtar Kelimeler:
Titanium dioxide nanoparricle, N-acetyl cysteine, neopterin, U937 monocytic cells, SH-SY5Y neuroblastoma cells, N-methyl-D-aspartate receptors, TUMOR-NECROSIS-FACTOR, N-ACETYLCYSTEINE, OXIDATIVE STRESS, TIO2 NANOPARTICLES, GLUTAMATE METABOLISM, TOXICITY, GLUTATHIONE, EXPRESSION, NMDA, CYSTEINE
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Ankara Üniversitesi Adresli:
Evet
Özet
Introduction: The toxicity of titanium dioxide nanoparticles (TiO(2)NPs) in neurons occurs by glutamate signaling via N-methyl-d-aspartate (NMDA) receptors. Although cellular uptake of TiO(2)NPs may lead to oxidative stress in macrophages, it is nor known whether TiO(2)NPs have toxic effects on U937 monocytic cell line.