The Significance of Thiol/Disulfide Homeostasis and Ischemia- modified Albumin Levels in Assessing Oxidative Stress in Obese Children and Adolescents

Mengen E., Ucakturk S. A., Kocaay P., KAYMAZ Ö., NEŞELİOĞLU S., EREL Ö.

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, cilt.12, sa.1, ss.45-54, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4274/jcrpe.galenos.2019.2019.0039
  • Dergi Adı: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.45-54
  • Anahtar Kelimeler: Obesity, children and adolescents, thiol/disulfide homeostasis, ischemia-modified albumin, REDUCED ANTIOXIDANT CAPACITY, THIOL-DISULFIDE HOMEOSTASIS, TYPE-2 DIABETES-MELLITUS, CHILDHOOD OBESITY, INFLAMMATION MARKERS, INSULIN-RESISTANCE, METABOLIC SYNDROME, PUBERTAL CHANGES, PLASMA, GLUTATHIONE
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: There is an association between obesity and several inflammatory and oxidative markers in children. In this study, we analyzed thiol/disulfide homeostasis and serum ischemia-modified albumin (IMA) levels for the first time in order to clarify and determine the oxidant/antioxidant balance in metabolically healthy and unhealthy children.