Historical epidemiology of hepatitis C virus (HCV) in selected countries

Bruggmann, P.; Berg, T.; Ovrehus, A.; Moreno, C.; Brandao Mello, C.; Roudot-Thoraval, F.; Marinho, R.; Sherman, M.; Ryder, S.; Sperl, J.; AKARCA, ULUS; Balik, İSMAİL; Bihl, F.; Bilodeau, M.; Blasco, A.; Buti, M.; Calinas, F.; Calleja, J.; Cheinquer, H.; Christensen, P.; Clausen, M.; Coelho, H.; Cornberg, M.; Cramp, M.; Dore, G.; Doss, W.; Duberg, A.; El-Sayed, M.; ERGÖR, GÜL; Esmat, G.; Estes, C.; Falconer, K.; Felix, J.; Ferraz, M.; Ferreira, P.; Frankova, S.; Garcia-Samaniego, J.; Gerstoft, J.; Giria, J.; Goncales, F.; Gower, E.; Gschwantler, M.; Guimaraes Pessoa, M.; Hezode, C.; Hofer, H.; Husa, P.; Idilman, RAMAZAN; Kaberg, M.; Kaita, K.; Kautz, A.; Kaymakoglu, S.; Krajden, M.; Krarup, H.; Laleman, W.; Lavanchy, D.; Lazaro, P.; Marotta, P.; Mauss, S.; Mendes Correa, M.; Muellhaupt, B.; Myers, R.; Negro, F.; Nemecek, V.; Ormeci, N.; Parkes, J.; Peltekian, K.; Ramji, A.; Razavi, H.; Reis, N.; Roberts, S.; Rosenberg, W.; Sarmento-Castro, R.; Sarrazin, C.; Semela, D.; Shiha, G.; Sievert, W.; Starkel, P.; Stauber, R.; Thompson, A.; Urbanek, P.; van Thiel, I.; Van Vlierberghe, H.; Vandijck, D.; Vogel, W.; Waked, I.; Wedemeyer, H.; Weis, N.; Wiegand, J.; Yosry, A.; Zekry, A.; Van Damme, P.; Aleman, S.; Hindman, S.

doi:10.1111/jvh.12247

Historical epidemiology of hepatitis C virus (HCV) in selected countries

Atıf İçin Kopyala

Bruggmann P., Berg T., Ovrehus A. L. H., Moreno C., Brandao Mello C. E., Roudot-Thoraval F., ...Daha Fazla

JOURNAL OF VIRAL HEPATITIS, cilt.21, ss.5-33, 2014 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 21
Basım Tarihi: 2014
Doi Numarası: 10.1111/jvh.12247
Dergi Adı: JOURNAL OF VIRAL HEPATITIS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.5-33
Anahtar Kelimeler: treatment, mortality, diagnosis, incidence, HCV, epidemiology, prevalence, hepatitis C, disease burden, INJECTING DRUG-USERS, BLACK-SEA REGION, GENOTYPE DISTRIBUTION, HEPATOCELLULAR-CARCINOMA, HIGH PREVALENCE, BLOOD-DONORS, RISK-FACTORS, ELEVATED AMINOTRANSFERASES, ORTHOPEDIC-SURGERY, GENERAL-POPULATION
Ankara Üniversitesi Adresli: Evet

Özet

Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3% in Austria, England and Germany to 8.5% in Egypt. The largest viremic populations were in Egypt, with 6358000 cases in 2008 and Brazil with 2106000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.