Vaginal bleeding and a giant ovarian cyst in an infant with 21-hydroxylase deficiency

Sahin N. M., Bayramoglu E., Cetinkaya S., Erdeve S. S., Karaman A., Akdogan M. P., ...Daha Fazla

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.31, sa.2, ss.229-233, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1515/jpem-2017-0235
  • Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.229-233
  • Anahtar Kelimeler: 21-hydroxylase deficiency, congenital adrenal hyperplasia, giant ovarian cyst, gonadotropin cascade, vaginal bleeding, CONGENITAL ADRENAL-HYPERPLASIA, FOLLICLE, NEONATE, AXIS
  • Ankara Üniversitesi Adresli: Hayır

Özet

Background: Increased adrenal androgen hormones in congenital adrenal hyperplasia (CAH) can rarely cause giant ovarian cysts in the neonatal period. Although the exact mechanism of the development of ovarian cysts is unknown, it is thought that increased androgen levels stimulate folicle development by increasing follicle stimulating hormone (FSH) levels.