The Growth Characteristics of Patients with Noonan Syndrome: Results of Three Years of Growth Hormone Treatment: A Nationwide Multicenter Study

ŞIKLAR, ZEYNEP; Genens, Mikayir; Poyrazoglu, Sukran; BAŞ, Firdevs; Darendeliler, Feyza; Bundak, Ruveyde; AYCAN, ZEHRA; Erdeve, Senay; Cetinkaya, Semra; Guven, Ayla; ABALI, Saygın; Atay, Zeynep; DEMİRCİOĞLU, SERAP; Kara, Cengiz; Yilmaz, Gulay; Akyurek, Nesibe; ABACI, AYHAN; Celmeli, Gamze; Sari, Erkan; Bolu, Semih; Korkmaz, Huseyin; Simsek, Enver; Catli, Gonul; Buyukinan, Muammer; Cayir, Atilla; EVLİYAOĞLU, Saadet; Isguven, Pinar; ÖZGEN, İLKER; HATİPOĞLU, NİHAL; ELHAN, ATİLLA; BERBEROĞLU, MERİH

doi:10.4274/jcrpe.3013

The Growth Characteristics of Patients with Noonan Syndrome: Results of Three Years of Growth Hormone Treatment: A Nationwide Multicenter Study

Atıf İçin Kopyala

ŞIKLAR Z., Genens M., Poyrazoglu S., BAŞ F., Darendeliler F., Bundak R., ...Daha Fazla

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, cilt.8, sa.3, ss.305-312, 2016 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 8 Sayı: 3
Basım Tarihi: 2016
Doi Numarası: 10.4274/jcrpe.3013
Dergi Adı: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.305-312
Anahtar Kelimeler: Noonan syndrome, growth hormone treatment, growth, CLINICAL-FEATURES, CHILDREN, THERAPY, HEIGHT, MUTATIONS, DIAGNOSIS
Ankara Üniversitesi Adresli: Evet

Özet

Objective: Noonan syndrome (NS) is a multisystem disorder, and short stature is its most striking manifestation. Optimal growth hormone (GH) treatment for NS is still controversial. In this study, using a nationwide registration system, we aimed to evaluate the growth characteristics and the clinical features of NS patients in Turkey and their growth response to GH treatment.