Pediatric Reference Intervals for Complete Blood Count Parameters in Healthy Turkish Infants and Children


Özgen Ü., ORHON F., KESKİNDEMİRCİ G., ÇUHACI ÇAKIR B., Kondolot M., Almış H., ...Daha Fazla

International Journal of Laboratory Hematology, 2026 (SCI-Expanded, Scopus) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1111/ijlh.70068
  • Dergi Adı: International Journal of Laboratory Hematology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
  • Anahtar Kelimeler: complete blood count, reference value, Turkish infant and children
  • Ankara Üniversitesi Adresli: Evet

Özet

Purpose: The study aims to provide reference ranges of complete blood count (CBC) parameters in healthy children in Türkiye. Methods: Children aged 1 month to −18 years who were administered to the Well Child Outpatients Clinics of Department/Unit of Social Pediatrics in 10 centers in different regions of Türkiye were included in the study. Complete blood count measurements were collected from these centers. Results: A total of 24 115 healthy infants and children (12 204 males and 11 911 females) aged 1 month–18 years old were enrolled. Mean and median values of the red blood cell, white blood cell, and platelet parameters according to the age groups are presented in this study. In addition, the nonparametrically determined CBC reference intervals (RIs) corresponding to the 2.5th to 97.5th percentile, stratified by age and sex were provided. Conclusion: This is the first study that established RIs for hematological parameters in Turkish children younger than 18 years old. These data provide a more reliable basis for hematological evaluation across all pediatric healthcare disciplines in Türkiye.