Ulcerative IgA vasculitis in the setting of warfarin therapy.

Kalay-Yildizhan İ., AKAY B. N., BOYVAT A., HEPER A.

Dermatology online journal, cilt.26, sa.9, 2020 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 9
  • Basım Tarihi: 2020
  • Dergi Adı: Dermatology online journal
  • Derginin Tarandığı İndeksler: Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Anahtar Kelimeler: Adult, Anticoagulant drugs, Henoch-Schönlein purpura, IgA, Vasculitis, Warfarin
  • Ankara Üniversitesi Adresli: Evet

Özet

© 2020 Dermatology Online Journal. All rights reserved.Henoch-Schönlein purpura (HSP) is a small vessel vasculitis characterized by the presence of vascular immunoglobulin A deposition that usually presents as non-thrombocytopenic palpable purpura. It primarily affects children and is less common in adults. The incidence of hemorrhagic necrotic skin lesions increases with age, similarly to renal involvement. Warfarin is a widely used oral anticoagulant drug that has rarely been associated with leukocytoclastic vasculitis and allergic interstitial nephritis. We report a patient with HSP who presented with cutaneous ulcerative plaques and proteinuria in the setting of warfarin therapy. We would like to raise the awareness of this potential adverse effect of warfarin for prompt diagnosis.