Diagnosis of intestinal ischemia by measurement of serum phosphate and enzyme changes and the effectiveness of vitamin E treatment Serum fosfor ve enzim degisiklikleri yardimiyla intestinal iskemi tanisinin konmasi ve tedavi icin kullanilan e vitamininin etkinliginin belirlenmesi

Uncu H., Uncu G., Ilcol Y., Aker Y.

Turkish Journal of Gastroenterology, vol.10, no.3, pp.272-275, 1999 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 3
  • Publication Date: 1999
  • Journal Name: Turkish Journal of Gastroenterology
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.272-275
  • Keywords: Hepatic enzyme, Intestinal ischemia, Phosphate, Vitamin E
  • Ankara University Affiliated: No

Abstract

Ischemia of the intestine is associated with acute injury of other organs and early diagnosis and surgical intervention is necessary to reduce morbidity and mortality. The aim of this study was to investigate changes in serum enzymes and phosphate values following diagnosis of intestinal ischemia and to determine the effects of vitamin E on its treatment. Twenty New Zealand rabbits were seperated randomly into two groups. In the first group, superior mesenteric arteries were ligated, blood samples taken and ALT, AST, ALP, LDH, CK and P levels measured after one hour of ischemia. In the second group, intestinal ischemia was induced, vitamin E injected following ten minutes of ischemia and the same biochemical investigations performed after one hour of ischemia. There was no significant difference between the results of the two groups. The laboratory parameters may be of benefit in the early diagnosis of intestinal ischemia. However, the results of these parameters were not changed by the use of vitamin E as an antioxidant.