Tendency of K562 Chronic Myeloid Leukemia Cells Towards Cell Reprogramming
TURKISH JOURNAL OF HEMATOLOGY, vol.35, no.4, pp.260-264, 2018 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 35 Issue: 4
- Publication Date: 2018
- Doi Number: 10.4274/tjh.2018.0106
- Journal Name: TURKISH JOURNAL OF HEMATOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.260-264
- Keywords: Induced pluripotent stem cells, Chronic myeloid leukemia, K562, Disease modeling, Cell reprogramming, PLURIPOTENT STEM-CELLS, CANCER-CELLS, IPS CELLS, GENERATION
- Open Archive Collection: AVESIS Open Access Collection
- Ankara University Affiliated: Yes
Abstract
Objective: Cancer cell reprogramming is a potential tool to study cancer progression, disease pathology, and drug sensitivity. Prior to performing cancer reprogramming studies, it is important to evaluate the stemness predisposition of cells that will be reprogrammed. We performed a proof-of-concept study with chronic myeloid leukemia K562 cells in order to evaluate their tendency for cancer cell reprogramming.