Tendency of K562 Chronic Myeloid Leukemia Cells Towards Cell Reprogramming

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YILMAZER AKTUNA A.

TURKISH JOURNAL OF HEMATOLOGY, cilt.35, sa.4, ss.260-264, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.4274/tjh.2018.0106
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.260-264
  • Anahtar Kelimeler: Induced pluripotent stem cells, Chronic myeloid leukemia, K562, Disease modeling, Cell reprogramming, PLURIPOTENT STEM-CELLS, CANCER-CELLS, IPS CELLS, GENERATION
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Cancer cell reprogramming is a potential tool to study cancer progression, disease pathology, and drug sensitivity. Prior to performing cancer reprogramming studies, it is important to evaluate the stemness predisposition of cells that will be reprogrammed. We performed a proof-of-concept study with chronic myeloid leukemia K562 cells in order to evaluate their tendency for cancer cell reprogramming.