Periampullary localized pancreatic intraepithelial neoplasia-3 (PanIN-3): Evaluation with contrast-enhanced MR cholangiography (MRCP)

ALGIN O., Ozmen E., Ersoy P., Karaoglanoglu M.

Radiology and Oncology, cilt.45, sa.4, ss.300-303, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.2478/v10019-011-0035-2
  • Dergi Adı: Radiology and Oncology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.300-303
  • Anahtar Kelimeler: carcinoma, magnetic resonance cholangiography, magnetic resonance imaging, multidetector computed tomography, pancreatic cysts, pancreatic intraepithelial neoplasia
  • Ankara Üniversitesi Adresli: Hayır

Özet

Background. The early determination of premalignant lesions of pancreas can prevent unnecessary excessive surgical procedures and can reduce morbidity and mortality. Pancreatic intraepithelial neoplasia-3 (PanIN-3) is a preinvasive form of adenocarcinoma (carcinoma in situ). PanINs have not taken place in the literature of radiology yet, it should be considered in differential diagnosis of pancreatic cystic lesions.Case report. A patient with preliminary diagnosis of chronic cholecystitis who had choledocolithiasis and periampullary pancreatic cyst detected by noncontrast-enhanced (NCE) and contrast-enhanced (CE) magnetic resonance cholangiography (MRCP) is presented. Pathological examination results of gallbladder and pancreatic cyst were reported as gallbladder adenocarcinoma and PanIN-3, respectively.Conclusions. Pancreatic cystic lesions with thin septa which enhances slightly with the administration of contrast material may represent PanIN-3. In patients with cystic pancreatic lesion localized at periampullary region, using CE-MRCP together with NCE-MRCP could be useful in the evaluation of pancreatic cystic masses as well as other abdominal pathologies.