The comparison of full G and N gene sequences from turkish rabies virus field strains

Atici Y. T., Oğuzoğlu T. Ç.

VIRUS RESEARCH, cilt.315, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 315
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.virusres.2022.198790
  • Dergi Adı: VIRUS RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: Rabies virus, Field strains, N and G genes, Turkey, MOLECULAR CHARACTERIZATION, COMPLETE GENOME, ORAL VACCINATION, GLYCOPROTEIN, DOG, PATHOGENICITY, POSITION-333, DETERMINANT, PROVINCE, ARGININE
  • Ankara Üniversitesi Adresli: Evet

Özet

The rabies infection is a zoonotic viral disease in humans and is spread by both wild and domestic carnivores. This study aimed to molecularly characterize the field strains of the rabies virus circulating in Turkey between 2013 and 2020. Brain samples obtained from 16 infected animals (eight cattle, one donkey, three foxes, three dogs, and one marten) were tested. Full nucleoprotein (N) and glycoprotein (G) gene sequences were used to determine the genetic and antigenic characteristics of the rabies virus field strains. The phylogenetic analyses revealed that the 16 field strains identified in Turkey belonged to the Cosmopolitan lineage.