A novel atropine electrochemical sensor based on silver nano particle-coated Spirulina platensis multicellular blue-green microalga

Ameen F., Hamidian Y., Mostafazadeh R., Darabi R., ERK N., Islam M. A., ...Daha Fazla

Chemosphere, cilt.324, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 324
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1016/j.chemosphere.2023.138180
  • Dergi Adı: Chemosphere
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aerospace Database, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), Artic & Antarctic Regions, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, Communication Abstracts, Compendex, EMBASE, Environment Index, Food Science & Technology Abstracts, Geobase, Greenfile, MEDLINE, Metadex, Pollution Abstracts, Public Affairs Index, Veterinary Science Database, Civil Engineering Abstracts
  • Anahtar Kelimeler: 1-Hexyl-3 methylimidazolium hexafluorophosphate ion liquid, Anticholinergic drug, Atropine sulfate ampoule, Carbon paste electrode, Silver electroless, Voltammetry method
  • Ankara Üniversitesi Adresli: Evet

Özet

In this work, Atropine as the anticholinergic drug was measured using the environmentally friendly sensor. In this regard, Self-cultivated Spirulina platensis with electroless silver was employed as a powder amplifier in carbon paste electrode modification. Also, 1-Hexyl-3 methylimidazolium Hexafluorophosphate (HMIM PF6) ion liquid as a conductor binder was used in the suggested electrode construction. Atropine determination was investigated by voltammetry methods. According to voltammograms, the electrochemical behavior of atropine depends on pH, and pH 10.0 was used as the optimal condition. Moreover, the diffusion control process for the electro-oxidation of atropine was verified by the scan rate study, so the diffusion coefficient (D∼ 3.0136×10−4 cm2/sec) value was computed from the chronoamperometry study. Furthermore, responses of the fabricated sensor were linear in the concentration range from 0.01 to 800 μM, and the lowest detection limit of the Atropine determination was obtained at 5 nM. Moreover, the stability, reproducibility, and selectivity factors of the suggested sensor were confirmed by the results. Finally, the recovery percentages for atropine sulfate ampoule (94.48–101.58), and water (98.01–101.3) approve of the applicability of the proposed sensor to Atropine determination in real samples.