Effects of phenytoin injection on vocal cord healing after mechanical trauma: An experimental study

Tokgoz S. A., Saka C., Akin I., Koybasioglu F., Kilicaslan S., ÇALIŞKAN M., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.49, no.5, pp.1577-1581, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 5
  • Publication Date: 2019
  • Doi Number: 10.3906/sag-1903-63
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1577-1581
  • Keywords: Phenytoin, vocal cord, wound healing, rat, FIBROBLAST-GROWTH-FACTOR, TOPICAL PHENYTOIN, FOLD INJURY, STEM-CELLS, RAT, PREVENTION, TERM
  • Ankara University Affiliated: Yes

Abstract

Background/aim: Phenytoin is an anticonvulsant drug which causes fibroblast proliferation, collagen synthesis, and an increase in epidermal growth factor. Therefore, the aim of the present study is to evaluate the effect of phenytoin injection on the wound healing process in rats with vocal cord injury by histopathological methods.