Effects of phenytoin injection on vocal cord healing after mechanical trauma: An experimental study

Tokgoz S. A., Saka C., Akin I., Koybasioglu F., Kilicaslan S., ÇALIŞKAN M., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.49, sa.5, ss.1577-1581, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 5
  • Basım Tarihi: 2019
  • Doi Numarası: 10.3906/sag-1903-63
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1577-1581
  • Anahtar Kelimeler: Phenytoin, vocal cord, wound healing, rat, FIBROBLAST-GROWTH-FACTOR, TOPICAL PHENYTOIN, FOLD INJURY, STEM-CELLS, RAT, PREVENTION, TERM
  • Ankara Üniversitesi Adresli: Evet

Özet

Background/aim: Phenytoin is an anticonvulsant drug which causes fibroblast proliferation, collagen synthesis, and an increase in epidermal growth factor. Therefore, the aim of the present study is to evaluate the effect of phenytoin injection on the wound healing process in rats with vocal cord injury by histopathological methods.