Co-administration of sodium hydrosulfide and tadalafil modulates hypoxia and oxidative stress on bladder dysfunction in a rat model of bladder outlet obstruction.

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Yilmaz-Oral D., Kaya-Sezginer E., Asker H., Gur S.

International braz j urol : official journal of the Brazilian Society of Urology, cilt.48, sa.6, ss.971-980, 2022 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 48 Sayı: 6
• Basım Tarihi: 2022
• Doi Numarası: 10.1590/s1677-5538.ibju.2022.0207
• Dergi Adı: International braz j urol : official journal of the Brazilian Society of Urology
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
• Sayfa Sayıları: ss.971-980
• Anahtar Kelimeler: Prostatic Hyperplasia, Urinary Bladder, Overactive, Hydrogen Sulfide, Tadalafil, HYDROGEN-SULFIDE, NITRIC-OXIDE, MECHANISM
• Ankara Üniversitesi Adresli: Evet

Özet

Purpose: This study aimed to assess the possible healing effect of combination treatment with a hydrogen sulfide (H2S) donor, sodium hydrosulfide (NaHS) plus tadalafil on partial bladder outlet obstruction (PBOO)-induced bladder dysfunction.