Co-administration of sodium hydrosulfide and tadalafil modulates hypoxia and oxidative stress on bladder dysfunction in a rat model of bladder outlet obstruction.

Yilmaz-Oral D., Kaya-Sezginer E., Asker H., Gur S.

International braz j urol : official journal of the Brazilian Society of Urology, cilt.48, sa.6, ss.971-980, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 6
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1590/s1677-5538.ibju.2022.0207
  • Dergi Adı: International braz j urol : official journal of the Brazilian Society of Urology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.971-980
  • Anahtar Kelimeler: Prostatic Hyperplasia, Urinary Bladder, Overactive, Hydrogen Sulfide, Tadalafil, HYDROGEN-SULFIDE, NITRIC-OXIDE, MECHANISM
  • Ankara Üniversitesi Adresli: Evet

Özet

Purpose: This study aimed to assess the possible healing effect of combination treatment with a hydrogen sulfide (H2S) donor, sodium hydrosulfide (NaHS) plus tadalafil on partial bladder outlet obstruction (PBOO)-induced bladder dysfunction.