Co-administration of sodium hydrosulfide and tadalafil modulates hypoxia and oxidative stress on bladder dysfunction in a rat model of bladder outlet obstruction.

Yilmaz-Oral, Didem; Kaya-Sezginer, ECEM; Asker, Heba; Gur, Serap

doi:10.1590/s1677-5538.ibju.2022.0207

Co-administration of sodium hydrosulfide and tadalafil modulates hypoxia and oxidative stress on bladder dysfunction in a rat model of bladder outlet obstruction.

Yilmaz-Oral D., Kaya-Sezginer E., Asker H., Gur S.

International braz j urol : official journal of the Brazilian Society of Urology, vol.48, no.6, pp.971-980, 2022 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 48 Issue: 6
Publication Date: 2022
Doi Number: 10.1590/s1677-5538.ibju.2022.0207
Journal Name: International braz j urol : official journal of the Brazilian Society of Urology
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
Page Numbers: pp.971-980
Keywords: Prostatic Hyperplasia, Urinary Bladder, Overactive, Hydrogen Sulfide, Tadalafil, HYDROGEN-SULFIDE, NITRIC-OXIDE, MECHANISM
Ankara University Affiliated: Yes

Abstract

Purpose: This study aimed to assess the possible healing effect of combination treatment with a hydrogen sulfide (H2S) donor, sodium hydrosulfide (NaHS) plus tadalafil on partial bladder outlet obstruction (PBOO)-induced bladder dysfunction.