Akademik Veri Yönetim Sistemi
Europeaan Respiratoru Society Congress, Barcelona, İspanya, 4 - 06 Eylül 2022, cilt.60, ss.1443
We aimed to evaluate the prognostic significance of MELD-XI score and SOFA score in patients with different etiologies admitted to the ICU for respiratory failure.
Out of 128 patients admitted to the intensive care unit with respiratory failure between September and December 2019, a total of 90 patients (69.6±18.2 years, 41 males) with etiologies of COPD exacerbation (n=36), acute cardiogenic pulmonary edema (n=18), acute PTE (n=14), pneumonia (n= 22) were included. DM, HT, coronary artery disease, arrhythmia, valvular heart disease, kidney failure, liver failure, cerebrovascular disease, pulmonary HT comorbidities were recorded.
31 patients died in ICU follow-up. MELD-XI and SOFA score were found to be associated with mortality in the whole group. Univariate Cox regression analysis MELD-XI for all patients was associated with increased mortality in the ICU (HR 1.09, 95% CI 1.06-1.12; p=0.01). In multivariate analysis, MELD-XI (1.03; 95%CI 1.01–1.05; p=0.01), creatinin (1.05; 95%CI 1.03–1.08, p=0.02), and PaO2 (HR 1.04, 95%CI 1.01–1.06; p = 0.01) were determined as independent variables. There was no difference in mortality estimation between SOFA score and MELD-XI score in the whole group. Patients with a high MELD-XI score (≥12) had higher mortality rates (47.5% vs 24%, p=0.01) and had more than three comorbidity rates (35% vs 14%, p=0.01). There was no difference between the MELD-XI scores of different etiologies.
MELD-XI is an important marker of ICU mortality in patients with respiratory failure. The MELD-XI score was as effective as the SOFA score in predicting mortality. Patients with multiple comorbidities have higher MELD-XI scores.