Clinical approach on challenge and desensitization procedures with aspirin in patients with ischemic heart disease and nonsteroidal anti-inflammatory drug hypersensitivity

Cortellini, G.; Romano, A.; Santucci, A.; Barbaud, A.; BAVBEK, SEVİM; Bignardi, D.; Blanca, M.; Bonadonna, P.; Costantino, M.; Laguna, J.; Lombardo, C.; Losappio, L.; Makowska, J.; Nakonechna, A.; Quercia, O.; Pastorello, E.; Patella, V.; Terreehorst, I.; Testi, S.; Cernadas, J.; Elera, J.; Lippolis, D.; Voltolini, S.; Grosseto, D.

doi:10.1111/all.13068

Clinical approach on challenge and desensitization procedures with aspirin in patients with ischemic heart disease and nonsteroidal anti-inflammatory drug hypersensitivity

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Cortellini G., Romano A., Santucci A., Barbaud A., BAVBEK S., Bignardi D., ...More

ALLERGY, vol.72, no.3, pp.498-506, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 72 Issue: 3
Publication Date: 2017
Doi Number: 10.1111/all.13068
Journal Name: ALLERGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.498-506
Keywords: aspirin, challenge procedure, desensitization procedure, nonsteroidal anti-inflammatory drugs hypersensitivity, CORONARY-ARTERY-DISEASE, RAPID DESENSITIZATION, ANTIPLATELET THERAPY, PROVOCATION TESTS, SENSITIVITY, INTOLERANCE, MANAGEMENT, DIAGNOSIS, HISTORY, ALLERGY
Ankara University Affiliated: Yes

Abstract

Background: Hypersensitivity to acetylsalicylic acid (ASA) constitutes a serious problem for subjects with coronary artery disease. In such subjects, physicians have to choose the more appropriate procedure between challenge and desensitization. As the literature on this issue is sparse, this study aimed to establish in these subjects clinical criteria for eligibility for an ASA challenge and/or desensitization.