Research Information System
Anestezi Dergisi, vol.19, no.3, pp.137-153, 2011 (Scopus)
In modern anesthesiology, combined usage of different drugs and techniques has been increasingly accepted. Addition of intravenous opioids and hypnotics to inhalation agents has become a method that gives the patient a more comfortable, secure, economic anesthesia, and faster recovery. During application of this method, it is important to know the interaction of the agents with each-other, with the patient, and with the drugs and the herbal supplements that the patient has been using. For this reason it is necessary to know the drug interaction mechanisms and their possible beneficial and detrimental effects. There is no direct answer to the question what the best agent and technique combination is, because there are many factors that contribute to the interaction. It is known that, as the number of agents increase, the interaction becomes unavoidable. Therefore, with a good history of the surgical patient, decision to stop, change or continue the drugs, with the knowledge of the effects of the agents that are used during the surgery, evaluation of their possible reactions and necessary precautions will increase safety.