Effects of papaverine on healing of colonic anastomosis in rats

Basceken S. I., Sevim Y., AKYOL C., ÇİÇEK E., Aydin F., KOCAAY A. F., ...Daha Fazla

EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA, cilt.49, sa.4, ss.158-164, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s10353-017-0481-1
  • Dergi Adı: EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.158-164
  • Anahtar Kelimeler: Ischemia-reperfusion injury, Anastomotic leak, Papaverine, ISCHEMIA-REPERFUSION INJURY, INTRAARTERIAL PAPAVERINE, CEREBRAL VASOSPASM, SMOOTH-MUSCLE, RISK, INFECTION, SURGERY, OXYGEN
  • Ankara Üniversitesi Adresli: Evet

Özet

Background Anastomotic leak is the most devastating complication after colorectal surgery, and the blood supply is a very important factor in anastomotic healing. Papaverine is a vasodilatory and antispasmodic agent which has been used in many ischemic conditions because of its potentially protective effects. The aim of this study is to investigate the effects of papaverine on healing colon anastomosis.