Akademik Veri Yönetim Sistemi
Neurourology and Urodynamics, 2026 (SCI-Expanded, Scopus)
Objective: To compare different treatment options for giggle incontinence (GI) and to identify clinical and demographic factors associated with complete treatment response (CTR) to a structured management protocol. Materials and Methods: We evaluated patients treated for GI in our outpatient clinic (2010–2025). Those who failed to achieve CTR and required methylphenidate were divided into two groups: Group 1 received standard urotherapy plus anticholinergics, and Group 2 received standard urotherapy plus biofeedback (BF). Results: A total of 133 patients were included in the study, Group 1 n = 63 and Group 2 n = 70. Initially, characteristics of patients with CTR with partial and non-responders, multivariate analysis revealed that admission at post-pubertal age, female sex, and a positive family history were significantly associated with complete response for both Group 1&2. However, no significant association was found with body mass index (BMI), Dysfunctional Voiding and Incontinence Symptoms Score (DVISS), constipation or enuresis. As a secondary outcome, response to methylphenidate was assessed. CTR rates were similar at 1 and 3 months, but at 6- and 12-months Group 2 showed significantly higher CTR compared to Group 1 (57% vs. 83% and 51% vs. 91%, p < 0.05). Conclusions: For treatment of GI, post-pubertal age, female gender, and a positive family history were found to be associated with a CTR both for anticholinergics and BF. In refractory GI cases where methylphenidate was added to the treatment, a history of BF therapy was associated with long-term CTR.