Optical Coherence Tomography Angiography Findings in Long-Term Follow-up of Leber's Hereditary Optic Neuropathy: Report of Two Cases

BİNGÖL KIZILTUNÇ P., Bilen F. T., ATİLLA H.

TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY, cilt.50, sa.5, ss.313-316, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: 5
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4274/tjo.galenos.2020.86300
  • Dergi Adı: TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.313-316
  • Anahtar Kelimeler: Leber's hereditary optic neuropathy, optical coherence tomography, optical coherence tomography angiography, retinal nerve fiber layer
  • Ankara Üniversitesi Adresli: Evet

Özet

Leber's hereditary optic neuropathy (LHON) is thought to be a neurovascular disease due to presence of vascular changes in asymptomatic patients. Here we present 2 patients in whom optical coherence tomography angiography (OCTA) imaging demonstrated capillary dropout areas and decreased radial peripapillary capillary (RPC) density in the quadrants that had thinner retinal nerve fiber layer (RNFL) in OCT images. Progressive decrease in RNFL and RPC density were shown in each patient at month 12 and 30 of follow-up. Following up patients with OCTA imaging in the future will provide insight into the pathogenesis and prognosis of LHON.